HH5561 Health Economics and Decision Modelling Assignment, UOG, UK
The assignment involves analyzing a decision model provided in Excel worksheets. Key tasks include:
Programming the Decision Model
Use the provided structure and data for a stylized testing intervention.
Performing Sensitivity Analysis
Assess how different inputs influence the model’s outcomes.
Reporting Results
Write a short report summarizing findings from the model and analysis.
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Submission Details
Report Word Limit: Up to 1,000 words, divided into:
Results (~800 words): Present base case results and sensitivity analysis.
Conclusions (~200 words): Provide decision-making insights based on the analysis.
References: Use Harvard Referencing Style consistently.
Formatting Guidelines:
Use clear headings, tables, and figures where necessary.
Ensure tables and figures contribute to the analysis and are legible.
Avoid redundant data in visual elements.
Worksheets Provided
Introduction: Overview of assessment details.
Conceptual Model: Diagram of a decision tree representing the model structure.
Data: Input parameters for the model, including clinical, cost, and outcome details.
Decision Problem
Population: Patients admitted to hospital with suspected severe infection.
Intervention: Adding a test to the clinical pathway to guide antibiotic use.
Comparator: Existing clinical practice without the test.
Outcomes: Costs, Quality Adjusted Life Years (QALYs), incremental cost-effectiveness ratio (ICER), and incremental monetary net benefit (INMB).
Model Summary
Structure: Decision tree.
Time Horizon: 12 months.
Perspective: Health care payer (Canadian dollars).
Follow-up Periods:
1 Month: Assess outcomes post-hospital stay.
12 Months: Evaluate infection resolution and symptoms.
Potential Patient States:
Alive (with/without complications).
Dead (with/without antibiotics)
Clinical Parameters
Parameter
Value (Mean)
Standard Error
Notes
Mortality
Baseline (current practice)
0.15
0.02
1-month follow-up
RR (Testing strategy)
0.9
0.03
Mortality after complications
0.3
0.06
12-month follow-up
Mortality (no complications)
0.05
0.01
Complications
Baseline (current practice)
0.25
0.04
RR (Testing strategy)
0.75
0.12
Antibiotic Initiation
Baseline (current practice)
0.85
0.07
RR (Testing strategy)
0.65
0.09
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Cost Parameters (CAN $)
Parameter
Value (Mean)
Standard Error
Notes
Testing Costs
$250.00
NA
Antibiotics
$50.00
NA
Inpatient Stay (Complications)
$17,500.00
500
At 1 month
Inpatient Stay (Patient Died)
$12,500.00
350
At 1 month
Inpatient Stay (No Complications)
$4,500.00
300
At 1 month
Outcome Parameters
Parameter
Value (Mean)
Standard Error
Notes
Alive at 1 Month (QALY)
0.1
NA
Alive at 12 Months (QALY)
0.75
NA
QALY Decrement for Complications
-0.05
NA
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